Case Control Studies


Subjects are chosen for case-control studies based on their illness status. This research was done in the past. A group of people who have the disease (the "case" group) is contrasted with a group of people who do not have the sickness (the "control" group). In a perfect world, the control group would come from the same population as the cases. The case-control study examines possible exposures that both groups (cases and controls) may have experienced over the course of time. The exposed cases (A), exposed controls (B), unexposed cases (C), and unexposed controls are displayed in a 2 by 2 table (D). The odds ratio (OR), which is the ratio of the odds of exposure in the cases (A/C) to the odds of exposure in the controls (B/D), is the statistic created to measure association.


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